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Recent work

Hoces, D., Miguens Blanco, J. Hernandez-Lopez, R.A., A synthetic biology approach to engineering circuits in immune cells, Immunological Reviews (2023) - link 

Hernandez-Lopez,R.A., Yu, W., Cabral, K.A.*, Creasey, O.A.*, Lopez Pazmino, M.P., Tonai,Y., De Guzman, A., Mäkelä, A., Saksela, K., Gartner, Z.J., Lim, W.A “T cell circuits that sense antigen density with an ultrasensitive threshold”.

Science (2021).


Cell Research

Signal Transduction and Targeted Therapy

Annals of the New York Academy of Sciences

Cellular and Molecular Life Sciences

Huang, X., Williams, J.Z., Chang, R, Li, Z., Burnett, C.E., Hernandez-Lopez, R., Setiady, I., Gai, E., Patterson, D.M., Yu, W., Roybal, K.T., Lim, W.A.#, Desai, T.A.# “DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation”. Nature Nanotechnology (2020).


Ludington, W.B., Ishikawa, H., Serebrenik, Y.V., Ritter, A.*, Hernandez-Lopez, R.*, Gunzenhauser,J.*, Kannegaard, E., and Marshall, W.F. “A systematic comparison of mathematical models for inherent measurement of ciliary length: how a cell can measure length and volume”. Biophysical Journal (2015).

Ramirez-Cordero, B. , Toledano, Y., Cano-Sanchez, P., Hernandez-Lopez, R., Flores-Solis, D., Saucedo-Yanez, A, Chavez-Uribe, I., Brieba de Castro, L., and del Río-Portilla, F. “Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines”. Chemical research in toxicology (2014).

Gurrola Briones, G., Hernandez-Lopez, R., Rodriguez de la Vega, R., Varga, Z., Ferreira Batista, C., Salas-Castillo, S., Panyi, G., Del Rio-Portilla, F., and Possani, L. D. “Structure, function and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes”. Biochemistry (2012).

RedwineW. B. *, Hernandez-Lopez, R.*, Zou, S., Huang, J., Reck-Peterson, S. L., and Leschziner, A. E. “Structural basis for microtubule binding and release by dynein”. Science (2012).

Saucedo-Yanez, A., Flores-Solis, D., Rodriguez de la Vega, R., Ramirez-Cordero, B., Hernandez-Lopez, R., Cano-Sanchez, P., Noriega-Navarro, R., Garcia-Valdez, J., Coronas-Valderrama, F., de Roodt, A., Brieba de Castro, L., Possani, L. D., and del Río-Portilla, F. “New tricks of an old pattern: structural versatility of scorpion toxins with common cysteine spacing”. The Journal of Biological Chemistry (2012).

Chandramouli P., Hernandez-Lopez, R., Wang, H., and Leschziner, A. “Validation of the orthogonalt tilt reconstruction method with a biological test sample”. Journal of Structural Biology (2011).

* Equal contribution


Past work

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